Fluoxetine, also known under the trade name Prozac, is one of the most popular antidepressants in the group of selective serotonin reuptake inhibitors.
It was established in 1974 and after passing all the necessary security checks went into retail in 1987. Over the years, the market has confirmed high efficiency and has not lost its relevance to this day. The number of prescriptions for fluoxetine-containing antidepressants prescribed worldwide is measured in hundreds of millions.
Detailed academic article about this drug can be read on Wikipedia.
The operating principle of fluoxetine
The principle of fluoxetine can be in a highly simplified form, "on the fingers," can be represented as follows.
In our body there is a neurotransmitter – serotonin. It has an impact on many internal processes, including digestion and vascular tone, but primarily on our mental well-being – confidence, calm, the ability to enjoy life. If for some reason the level of serotonin is insufficient, a person may begin to experience depression, depression, complexes for contrived reasons and forever doubt himself.
Why the body may experience a serotonin deficiency is a complex and multifaceted question. We are also more interested in what can be done in order to bring its balance back to normal. A balance to normal in two ways – to increase the incoming flow or reduce the outgoing.
The incoming flow can be increased in a variety of ways – for example, by systematic sports or Eastern health practitioners, meditation. The problem is that often a person who lacks serotonin does not have the strength to force himself to do this, and then also wait for the results.
Another way to increase the incoming flow – the use of alcoholic beverages. Once in the body, alcohol causes a sudden release of serotonin, which improves mood, internal stiffness disappears and life for some time begins to seem more pleasant and colorful. And then intoxication passes, the level of serotonin falls back, there comes a need for repetition. The negative influence of alcohol on the ability to think and its general destructive effect on the body is obvious to everyone, but, unfortunately, for many people alcohol addiction is the only way to maintain their psycho-emotional state that is known and proven in practice for effectiveness.
But after all, serotonin is produced in any quantity by any organism! So, it is not necessary to interfere in the processes of its production – you can somehow try to slow down its elimination and come to a normalization of balance on this side. It is on this principle that the effect of fluoxetine is based – it initiates the reuptake of serotonin, preventing it from being eliminated as quickly as before. Coupled with the fact that in some amounts of serotonin anyway in the body is produced, this eventually leads to an increase in its quantity.
This path is much more benign, since we do not bring anything into the body beyond what it was and so, and it is much better controlled by the intensity of exposure – unlike the same alcohol, which provokes an excessively large single release of serotonin, or sports , the one-time effect of which is insufficient, and the cumulative effect is excessively extended over time.
In a more scientific language, the principle of action of fluoxetine and other drugs of the SSRI group is described in the instructions for them, and is more clearly shown in the video below.
Drugs with fluoxetine
There are currently many fluoxetine-based antidepressants available on the market under various trade names.
- Fluoxetine Acre
- Fluoxetine Hexal
- Fluoxetine hydrochloride
- Fluoxetine Lannaher
The best fluoxetine drug
Which drug is best on the market? In fact, this is a difficult question, because the basis of all of them is the same active ingredient – fluoxetine, and it is not clear what, apart from the trade name, one drug is different from the other. Therefore, it is recommended to start with one of the two most common brands in Russia – Fluoxetin-Kanon or Fluoxetin Lannaher. Both drugs have many positive reviews. In rare cases, it may turn out that the purchased drug is not “yours” due to the subjective sensations – this is completely normal, and in such a situation it is worth trying to simply change the fluoxetine of one brand to another.
And in order not to experience the flour of choice, you can immediately give preference to Prozac, the oldest fluoxetine-based drug that Eli Lilly, which originally discovered and registered the substance fluoxetine in 1974, introduced to the market. The only negative "Prozac" – a higher cost compared to peers.
Other candidates of the SSRI group can be attributed to fluoxetine analogs.
- Sertralin (Zoloft)
- Paroxetine (Paxil)
- Escitalopram ("Tsipralex")
- Fluvoxamine ("Fevarin")
The basis of their actions is the same principle, but different active ingredients. In the case of individual intolerance to fluoxetine or insufficiency of exposure, it is necessary to try other drugs.
In no case can you start taking a new SSRI drug less than 2 weeks after stopping the previous SSRI drug or antidepressants of the MAO inhibitor group. Ignoring this prescription will lead to the fact that the interactions of several different active ingredients of the SSRI group will overlap each other, which can provoke the serotonin syndrome – a very unpleasant and potentially deadly phenomenon.
Prescription for fluoxetine
Fluoxetine is dispensed from pharmacies by prescription, since the decision to prescribe antidepressants and other psychoactive drugs can only be made by a qualified specialist after personal consultation with the patient.
Can I Buy Fluoxetine Without a Prescription?
Nevertheless, it is quite possible to buy fluoxetine without even having a prescription. Since this drug has no euphoric effect and is not suitable for recreational use, and is not a precursor for the manufacture of narcotic drugs, it is not included in the list of medicines for medical use, subject to subject-quantitative accounting.
How to buy fluoxetine without a prescription
To purchase fluoxetine without a prescription, you need to give the impression of an adult sane person who controls himself and understands what he is doing.
It should be understood that the decision to dispense a drug without a prescription is primarily a moral issue. Therefore, it is likely that a pharmacy pharmacist will refuse to sell to a person who can be mistaken for a teenage boy or a young girl – because it’s no secret that girls are prone to fluoxetine for weight loss and not fully aware of the consequences of such behavior. which can lead to negative results.
Well-groomed appearance, age over 25 years, calm voice and lack of nervousness in behavior with 80% probability will ensure the acquisition of any prescription drug, even in the absence of a paper prescription on his hands.