Folacin during pregnancy

Description relevant to

Latin name: Folacin

  • ATH code: B03BB01
  • Active substance: Folic acid (Folic acid)
  • Manufacturer: Jadran Galenski Laboratorij (Republic of Croatia)
  • The tablet contains the drug: the active substance – folic acid – 5 mg, auxiliary components: lactose monohydrate, cellulose microcrystalline povidone, crospovidone and magnesium stearate.

    Release form

    Folacin is available in tablets with 5 mg of the active substance, packaged in 10, 20 or 30 pieces.

    Folacin during pregnancy

    pharmachologic effect

    The drug has a hematopoietic effect.

    Pharmacodynamics and pharmacokinetics

    Folacin belongs to the B vitamins. Once in the body, it turns into tetrahydrofolic acid, as a coenzyme involved in important metabolic processes and necessary for the full maturation of megaloblasts, as well as the formation of normoblasts. Deficiency folic acid leads to the development of megaloblastic type of blood formation. The normal intake of substances into the human body helps to stimulate erythropoiesis, improves synthesis amino acids, eg, methionine, serine, glycine, nucleic acids, purines and so on.

    Folacin during pregnancy

    During pregnancy folic acid protects the fetus from teratogenic and damaging factors. And also favors the normal maturation and activity of the placenta.

    After ingestion folic acid occurs in the gastrointestinal tract, almost immediately binding to plasma proteins. Then in the liver the substance is deposited and tetrahydrofolic acid is formed from it.

    This component passes through the placenta, BBB, and enters breast milk. The maximum concentration in the blood is reached within 30-60 minutes. The removal of the drug occurs unchanged or as metabolites through the kidneys, after about 5 hours

    Indications for use Folatsina

    The main indications for the use of Folacin are:

    • treatment and prevention of folic acid deficiency caused by unbalanced or malnutrition;
    • treatment and prevention of various types anemia against the background of a lack of body folic acid, for example, in the development of diseases and complications, lactation and of pregnancy and so on.

    In addition, the drug is prescribed to pregnant women to prevent the development of pathologies of the neural tube in the fetus.

    Contraindications

    • intolerance to the components of the drug;
    • malignant neoplasms;
    • pernicious anemia;
    • cobalamin deficiency.

    Side effects

    When treated with folacin and other drugs folic acid can develop allergic reactions as: itch, skin rashes, erythema and bronchospasm.

    You should also not exclude deviations in the activity of the gastrointestinal tract, for example: anorexia, nausea, bitter taste in the mouth, bloating and other.

    Instructions on Folacin (method and dosage)

    The drug is intended for ingestion. According to the instructions for use Folacin, in the treatment or prevention of folic acid deficiency used various dosages.

    For example, in the treatment of megaloblastic anemia, a daily dose of 5 mg is prescribed, and for the prevention of this condition – 2.5 mg.

    To prevent the development of fetal neural tube defects, it is recommended to take 2.5 mg over 4 weeks before the intended pregnancy. Then during the first trimester of pregnancy taking the drug continues.

    Perhaps the appointment and higher maintenance dosages, for example, patients with alcoholism, chronic infectious diseases and taking anticonvulsants.

    Overdose

    Cases of overdose are not established.

    Interaction

    Simultaneous reception with chloramphenicol, tetracyclines, neomycin or polymyxin leads to reduced suction folic acid.

    Folate reduces efficacy contraceptives, ethanol, sulfasalazine, glutethimide, cycloserine, methotrexate, primidine, phenytoin and so on.

    Also sometimes folic acid lowers plasma levels phenobarbital, primidone and phenytoin, causes an epileptic seizure.

    In addition, while taking colestyramine with folic acid marked decrease or change in absorption. For this reason folic acid recommended for use one hour before or after 4-6 hours from the moment of reception colestyramine.

    Terms of sale

    In pharmacies, the drug can be purchased without a prescription.

    Storage conditions

    Storage space should be protected from children, have a temperature not exceeding 25 ° C.

    Shelf life

    To counterparts Folatsina include: Mamifol, Folic Acid, Evitol, Flavinate and so on.

    Alcohol and Folacin

    Alcohol has been found to reduce absorption folic acid, therefore, its use is better to refuse.

    Folacin during pregnancy

    During pregnancy, folic acid is one of the most essential components for the female body. Moreover, Folacin is prescribed both during pregnancy planning and after its occurrence.

    It is established that this component is involved in the most important processes of the body: blood formation, development of nucleic and amino acids, metabolism, activity of the nervous, cardiovascular and other systems of the body.

    During pregnancy folic acid prescribed to ensure the normal formation and activity of the placenta, the development of the neural tube in the fetus and cell division. Also, this substance protects the embryo from negative and damaging effects, prevents the development of pathologies and contributes to the safe course of pregnancy.

    If there is a deficiency in the body folic acid, this increases the risk of premature birth, placental abruption, postpartum hemorrhage, vitamin deficiency in the newborn, and so on. Therefore, women are assigned folic acid or Folacin. Moreover, as shown by reviews during pregnancy, the need for this substance is constantly increasing, and its deficiency can be fully replenished only by taking special preparations.

    Reviews of Folacine

    As numerous reviews of Folacine show, it is prescribed to women when planning pregnancy and in the first months of this responsible period. Most women know that folic acid It is necessary for both the female body and the unborn child, so the obligatoriness of its reception does not cause any doubts.

    Also Folacin is very popular with nursing mothers. Quite often, mothers of newborn babies feel very weak and tired. After testing, deficiency is often found folic acid.

    According to experts, Folacin is a highly effective vitamin preparation that is actively used in clinical practice. Its main component is folic acid Included in the composition of vital medicines that are used in the treatment and as prevention of congenital malformations of the fetus, anemic conditions during lactation and pregnancy.

    Folacin price, where to buy

    You can buy the drug in almost every Russian pharmacy. The price of Folacin varies from 115 to 150 rubles.

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