Both gynecologists and endocrinologists know well how important it is to control the level of hormones in a woman, especially during pregnancy. At this time, almost all organs and systems of the body change the course of their work, tuning in to a new way. After all, for nine months their main task will be to ensure the normal development of the child and to maintain the healthy state of the future mother. Of course, affect these changes and the functioning of the thyroid gland. Violation of the level of hormones produced by it, in many respects affects the development and course of pregnancy.
The level of hormone TSH allows you to find out whether the pregnancy is developing normally or there are any abnormalities. This indicator is determined by blood tests taken from a vein. If the TSH is lowered or, conversely, elevated, the doctor will prescribe additional studies. They will help to find out what caused the deviation of the hormone level from the norm.
What is TTG?
To know what is at stake, you need to consider the hormones that are produced by the human thyroid gland. Thyrootropic hormone is responsible for the normal functioning of the anterior pituitary. It controls the development and functioning of the thyroid gland, as well as the production of triiodothyronine (T3) and thyroxine (T4). These hormones are very important for the normal functioning of the sexual and cardiovascular systems, are involved in metabolic processes and affect the psycho-emotional state of a person.
Why investigate the level of TSH?
Any fluctuations in the amount of hormones in the blood can cause various adverse health effects. It is very important to keep under control all significant indicators while carrying a child. Often there are situations when during this period hormones change. It happens that TSH is lowered during pregnancy. It is especially important to pay attention to such fluctuations, if a woman has previously experienced thyroid disease or had sad experiences associated with miscarriage or fetal dying.
The fact is that this hormone is very sensitive to pathological changes in the endocrine system. This is explained by one of the basic rules of medicine – the principle of negative feedback. If TTG is lowered, what does it mean? This indicates an increase in the level of free thyroxin. Conversely, with an increase in TTG decreases T4. Thus, knowing the basic parameters of the hormones produced by the thyroid gland, you can monitor the health of a woman, especially "interesting" position
TSH rates during pregnancy
The level of thyroid-stimulating hormone, determined by ELISA (enzyme-linked immunosorbent assay) in a woman’s blood, should be between 0.4 and 4 mU / liter. During pregnancy, these figures may slightly deviate from the norm. During this period, the level of TSH is constantly changing. Therefore, it is very difficult to derive any average parameters with which it should correspond. It is believed that the most TSH is lowered for a period of 10-12 weeks. But there are cases when it remains low throughout all nine months. Often, TSH is lowered in multiple pregnancies. However, minor deviations from the norm both in one and in the other direction are not considered pathology.
The effect of thyroid hormones on pregnancy
The endocrine system plays an important role. The thyroid gland produces triiodothyronine and thyroxin, and the pituitary gland directs this process. In its anterior lobe produced by the TSH, which controls the level of T3 and T4. Together with the blood flow, they get into almost all cells of the human body and take an active part in their vital activity.
The main function of triiodothyronine and thyroxine is the regulation and maintenance of basal metabolism. These hormones help regulate cell reproduction. During pregnancy, they have a stimulating effect on the corpus luteum, preventing the chance of miscarriage in the early period. In the same way as T3 and T4 affect the female body, they are also involved in the development of the fetus, especially in the formation of the brain.
Now that we know the importance of the normal level of hormones produced by the thyroid gland, for the mother and the unborn child, it is possible to understand why it is necessary to monitor the indicators of thyroxine and triiodothyronine. The doctor should be alerted to the situation when T4 is lowered (and TSH is elevated). In this case, a detailed study is assigned.
TSH when planning pregnancy
It would be a mistake to believe that the study of hormonal background is important only when a woman already has a baby under her heart. As mentioned earlier, thyroxin, triiodothyronine and TSH play an important role in human health. They affect the reproductive system. So, if the hormone TSH is lowered, it is not very scary. But if its level is increased simultaneously with a decrease in T3 and T4, the doctor may suggest a malfunction of the ovaries. And this, in turn, leads to a decrease in the probability of conceiving and carrying out a child.
Disturbed follicular production, the formation of the egg and the corpus luteum. Therefore, if a woman turns to the doctor with complaints about the impossibility of becoming pregnant, the endocrinologist will definitely prescribe an analysis of thyroid hormones. The ideal indicator for planning conception is the level of TSH, equal to 1.5 μIU / ml. This is the average level for an adult.
TTG lowered: what does this mean?
Unfortunately, it rarely happens that all tests are normal. Most often, at least one of them, but has deviations. For example, TSH lowered. What does it mean? As a rule, this test result should not alert the doctor. A slight decrease in the production of this hormone during pregnancy is absolutely normal. But in some cases this may be due to pathological conditions:
- If TSH is lowered during pregnancy, it is necessary to check the functioning of the pituitary gland.
- There is a small chance of Plummer syndrome.
- Benign tumors of the thyroid gland.
- Necrosis of the pituitary gland after childbirth.
- Elevated levels of hormones produced by the thyroid gland.
- Nervous overexcitement and overstrain.
So, if you are wondering "TSH lowered what does it mean"you should not look for information in the literature, it is better to immediately contact the endocrinologist. He will find out the reason for the changes and prescribe adequate treatment.
If the TSH is low, a woman may notice some symptoms, such as headache, heart palpitations, fever and upset stomach. But most often such changes are almost asymptomatic.
If tests have shown that the level of this hormone during pregnancy is increased, then doctors may order several additional studies, as this may be a sign of the following conditions:
- Work of adrenal glands is broken.
- There are mental illnesses.
- Problems with the pituitary gland.
- Elevated levels of thyroid hormones.
- Pituitary tumor.
- Renal failure.
- Gestosis in severe stage.
Symptoms of elevated TSH are low temperature, weakness, general fatigue, insomnia, pallor, and poor appetite. Visually, the neck looks thick.
Hormone T4: norms and deviations
Thyroxine is closely related to TSH, so tests are usually prescribed to study their level as a whole. T4 is one of the most important stimulators of cell division and regeneration in the body. The weight of a person largely depends on its quantity, since thyroxin is able to influence metabolic processes and protein synthesis. It is this hormone that determines the body’s need for vitamins, and also improves the absorption of carotene by the liver. In addition, it lowers cholesterol in the blood and prevents the appearance of plaques in the vessels of the brain. It is also very important for the work of the female reproductive system. In cases where the T4 level is lowered or elevated, problems often arise with the planning and course of pregnancy.
The norm of thyroxine is 9-22 pmol per liter. These indicators are applicable only to women, as they are higher for men. It is not always a deviation from the norm is a symptom of a serious disease, it is possible that temporary malfunctions occurred in the body. If you take a course of treatment, then the probability to bear and give birth to a healthy baby is very high.
The relationship between TSH and T4
The levels of hormones produced by the thyroid gland are closely intertwined. There are situations when TTG is lowered, T4 is increased. During normal operation of the pituitary and thyroid gland this should not be. Usually, if TSH is lowered, T4 is normal. This means that thyroxin suppresses thyrotropin production too much.